DOI: 10.54050/prj2724805 ISSN: 2632-4067

From ALS to multimodal neurodegenerative disease stratification: how HEREDITARY is building the foundations for personalised neurology

Gianmaria Silvello, Umberto Manera, Carlos Iglesias Losada

From ALS to multimodal neurodegenerative disease stratification: how HEREDITARY is building the foundations for personalised neurology

HEREDITARY develops privacy-preserving AI, semantic interoperability, and federated analytics technologies to study neurodegenerative diseases and the gut–brain axis across Europe. By integrating multimodal clinical, genomic, and im-aging data without moving sensitive records, the project aims to enable collaborative research, improve disease under-standing, and support future European health data infrastructures.