Focal Laser Photocoagulation for Large, Persistent Retinal Pigment Epithelial Detachment: A Case Series
Jun Young Ha, Jae Eun Kang, Yun Sik YangBackground and Objective:
This study aimed to describe outcomes of focal laser photocoagulation for large, persistent pigment epithelial detachment (PED).
Patients and Methods:
Ten eyes underwent focal 577-nm yellow laser photocoagulation at the peripheral PED margin and were reviewed for 6 months, longer when available.
Results:
Eight eyes achieved complete PED regression within 6 months: four predominantly serous, two mixed serous–fibrovascular with inactive type 1 choroidal neovascularization (CNV), and two with polypoidal choroidal vasculopathy. In mixed and polypoidal lesions, regression predominantly involved the serous component. The mean time to regression was 2.5 months, and best-corrected visual acuity improved from 0.41 to 0.25 logMAR. Two eyes with active type 1 CNV showed incomplete responses. Seven eyes maintained regression over a mean 49.9-month follow-up. No laser-related complications occurred.
Conclusion:
Focal laser photocoagulation was associated with regression of large, persistent PEDs, with responses influenced by lesion composition and neovascular activity. These preliminary findings require confirmation in larger controlled studies.