DOI: 10.1093/genetics/iyag247 ISSN: 1943-2631
FlyBase: Development and metamorphosis into the Alliance
Steven J Marygold, Helen Attrill, Gilberto dos Santos, L Sian Gramates, Alex McLachlan, Gillian Millburn, Christopher J Tabone, Rossana Zaru, , Norbert Perrimon, Gilberto dos Santos, Sian Gramates, Ian Longden, Jolene Seme, Christopher Tabone, Mark Zytkovicz, Nick Brown, Katja Röper, Helen Attrill, Aoife Larkin, Steven Marygold, Alex McLachlan, Gillian Millburn, Arzu Öztürk-Çolak, Clare Pilgrim, Rossana Zaru, Brian Calvi, Seth Campbell, Victor Strelets, Jim Thurmond, Richard Cripps, TyAnna Lovato, Giulia Antonazzo, Kris Broll, Madeline Crosby, Damien Goutte-Gattat, Victoria Jenkins, Thom Kaufman, Beverley Matthews, Susan Russo Gelbart, Pinglei ZhouAbstract
FlyBase (flybase.org) is an openly accessible, centralized resource for genetic, genomic and functional data about Drosophila melanogaster. This article describes recent updates to the curation and display of expression, functional and reagent data within FlyBase, including the incorporation of long-read RNA-seq data, the introduction of the 'Gene ToolKit' for identifying key genetic reagents, and new reports for protein complexes, metabolic pathways and combinations of split-GAL4 drivers. We also provide information on changes to our data archiving policy and guidance on how best to use AI methods to interrogate FlyBase. Finally, we give an update on the status of transitioning FlyBase into the Alliance of Genome Resources.