DOI: 10.1002/ejoc.202400316 ISSN: 1434-193X
Fluoroalkoxylating Reagents in Organic Synthesis: Recent Advances
Quande Wang, Mingxi ChenThe fluoroalkoxy groups (ORf) are widely used motifs in pharmaceutical and agrochemical fields due to their unique physicochemical properties including higher lipophilicity and increased metabolic stability. Thus, the high value of ORf‐containing derivatives has stimulated the development of fluoroalkoxylation reactions. In this review, we highlight the recent progress of various trifluoroalkoxylating reagents and their applications in organic synthesis in the past five years.