Financial Analysis of Transfusion Therapy: A Focus on Liquid Plasma and Fresh Frozen Plasma

Introduction/Objective

Fresh Frozen Plasma (FFP) is widely used in transfusions, but its short shelf life once thawed (5 days) can lead to wastage. Liquid Plasma (LQP), on the other hand, doesn't require thawing and, thus, has a longer shelf life (26 days), but also more expensive. Our project examines the cost-effectiveness of LQP versus FFP, with a focus on the waste resulting from FFP units expiration at our institution.

Methods/Case Report

Our methodology involves a comprehensive review of existing literature, focusing on the utility and advantages of liquid plasma incorporation in transfusion protocols, and strategies to mitigate the wastage of Fresh Frozen Plasma (FFP). We conducted a detailed evaluation of FFP usage and wastage data in 2022 at a level one trauma center in the Detroit metropolitan area, specifically pertaining to trauma and trauma activation cases.

Results (if a Case Study enter NA)

In 2022, our institution collectively consumed 2,595 units of Fresh Frozen Plasma (FFP). Of these, 1,024 units, or 39%, were wasted, and only 1,571 units, or 61%, were actually utilized. The average cost per unit of FFP was $40.8, resulting in a total expenditure of $105,876.

If the hospitals had used liquid plasma (LQP) instead of FFP, and assuming no wastage with LQP, the total cost would have been $88,133 (given the average cost of $56.1 per unit of LQP).

This implies that by switching to LQP from FFP, and by eliminating the wastage, the hospitals could have achieved a combined saving of $17,745 in 2022.

Conclusion

Our findings highlight the urgent need for more efficient plasma usage. Despite the higher cost of LQP per unit, the increased waste associated with FFP contributes to higher overall costs for hospitals, making liquid plasma a potentially more cost-effective option when considering waste reduction.