DOI: 10.1148/radiol.241482 ISSN: 0033-8419
“Fill States”: PET-derived Markers of the Spatial Extent of Alzheimer Disease Pathology
Elena Doering, Merle C. Hoenig, Kathrin Giehl, Verena Dzialas, Grégory Andrassy, Abdelmajid Bader, Andreas Bauer, David Elmenhorst, Johannes Ermert, Silke Frensch, Elena Jäger, Frank Jessen, Philipp Krapf, Tina Kroll, Christoph Lerche, Julia Lothmann, Andreas Matusch, Bernd Neumaier, Oezguer A. Onur, Alfredo Ramirez, Nils Richter, Frederik Sand, Lutz Tellmann, Hendrik Theis, Philip Zeyen, Thilo van Eimeren, Alexander Drzezga, Gérard N. Bischof,The spatial extent of amyloid, tau, and neurodegeneration, derived from PET imaging, has higher diagnostic performance for cognitive impairment severity compared with standardized uptake value ratios.