DOI: 10.14309/crj.0000000000002222 ISSN: 2326-3253

Fenbendazole-Associated Drug-Induced Liver Injury with Concomitant Use of Tauroursodeoxycholic Acid

Alexander Satinsky, Nancy Mayer, Charles Swanson, Brian Sasso

Influenced by the internet and social media, a growing number of individuals are taking hepatotoxic amounts of prescription and nonprescription drugs leading to drug-induced liver injuries (DILIs). We present a case of fenbendazole-associated DILI with concomitant use of tauroursodeoxycholic acid as an intended hepatoprotective agent. While fenbendazole-associated DILI has been increasingly reported, this case is unique due to associated tauroursodeoxycholic acid use, and, to our knowledge, represents the first published report of this exposure combination. This case builds on the growing literature of DILI due to nonprescription drugs and highlights the importance of patient-centered counseling.

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