Features of the dentoalveolar system in children with premature aging syndromes

Objective. To carry out a comprehensive analysis of dental manifestations and identify the features of the dental system in children with premature aging syndromes. Material and methods. The study included 7 patients with premature aging syndromes: a boy and a girl with Hutchinson—Gilford syndrome, 2 girls with Cockayne syndrome type A and B, one girl each with neonatal progeroid syndrome, Penttinen syndrome and mandibular hypoplasia, deafness, progeroid features and lipodystrophy (MDPL syndrome). During a clinical examination by a dentist, the condition of the hard tissues of the teeth, periodontal and oral mucosa was assessed. According to orthopantomography data, the condition of occlusion and dentition was assessed. Results. According to the results of the observations, a common pattern was revealed for all the examined patients: jaw hypoplasia and multiple caries. In patients with Hutchinson—Guilford and MDPL-syndrome, crowding and multiple carious lesions of the teeth were the most characteristic; for a patient with Penttinen syndrome, mandibular macrognathia, mesial occlusion and thickening of the mucous membrane of the frontal, sphenoid sinuses, a decrease in the cells of the latticed labyrinth;a feature of neonatal progeroid syndrome is the presence of neonatal incisors at birth, followed by hypo-/oligodontia or adentia. Conclusion. Knowledge of dento-mandibular anomalies in premature aging syndromes will allow dentists to timely detect pathologic changes in the dento-mandibular system and correct the dental status of patients with progeroid syndromes, which will significantly improve their quality of life.