FDG PET/CT in a Case of Marjolin Ulcer of the Scalp Over a Long-standing Burn Scar

Abstract

Marjolin ulcer is a malignant degeneration of previously injured skin, long-established scars, and wounds. This malignant transformation is most implicated in full-thickness burns; however, it may be associated with vaccination sites, pressure sores, venous stasis, and many other conditions causing chronic scar or wound formation. These lesions are aggressive and carry a poor prognosis. FDG PET/CT is an excellent diagnostic aid to differentiate these lesions from benign inflammation, to evaluate the primary malignant site and its extent and depth, and to evaluate metastasis.

Metabolic activity has been noted to be significantly higher in Marjolin ulcer than in benign conditions.