DOI: 10.4103/ajop.ajop_40_24 ISSN: 1687-9945

Factors affecting glycated hemoglobin level in diabetic children in Assiut Governorate

Amira M. Mohammed, Khaled H. Hassan, Mariam K.M. Soliman
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Background

Hyperglycemia, or high blood sugar, is a hallmark of type 1 diabetes mellitus (T1DM), an autoimmune condition that is caused by an insulin shortage brought on by the islets of Langerhans β -cell loss.

Aim

To investigate the factors affecting glycated hemoglobin (HbA1c) levels in children with T1DM at the Pediatric Department of Al-Azhar University.

Patients and methods

This cross-sectional study was conducted on 70 patients aged 1–18 years, who were diagnosed with T1DM and were currently dependent on insulin at the Pediatric Department of Al-Azhar University, the cases were collected from March 2023 through August 2023.

Results

HbA1c readings increased as BMI increased. Children with excess weight had a significantly higher HbA1c ( P <0.001) than underweight and normal weight individuals. Regarding puberty, the present study indicated that patients who had reached puberty had higher HbA1c levels (10.1±2.7) than patients who had not reached puberty (8.5±2.1) or patients who had normal weight (8.2±1.8).There was no statistically significant relationship ( P =0.288) between the related comorbidities and the HbA1c level.

Conclusion

This study showed the importance of HbA1c control in children with diabetes mellitus. The outcomes underscore the urgency of developing comprehensive strategies to enhance glycemic control and overall well-being. Overall, T1DM management requires personalized insulin therapy and consideration of lifestyle factors beyond HbA1c measurements to achieve better control and reduce complications.

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