Facial Vascular Lesions Treated with a 532-nm Laser: A Case Series and a Targeted Literature Review
Luca Guarino, Elena Zappia, Welisar Petrow, Giovanni Cannarozzo, Luca Gargano, Marco Virone, Alessandro Clementi, Marco Marcasciano, Mario Sannino, Ester Del Duca, Annunziata Dattola, Giovanni Pellacani, Steven Paul NisticòBackground:
Superficial facial vascular lesions such as telangiectasia and persistent erythema are common, and 532-nm laser platforms are widely used, although published evidence is heterogeneous. Our primary aim is to illustrate, in practical terms, how a 532-nm laser is applied across diverse superficial facial vascular phenotypes and to document the treatment parameters used, with a focused contextual review providing clinical background rather than an efficacy assessment. We describe 10 patients treated with a 532-nm platform, set against this focused review.
Methods:
Retrospective, single-arm, uncontrolled, non-consecutive descriptive case series of 10 outpatients (Fitzpatrick phototypes I–III) treated with a 532-nm platform (QuadroStarPRO GREEN); outcomes were assessed by paired clinical photographs and the patient-reported Global Aesthetic Improvement Scale (GAIS).
Results:
Photographic review suggested near-complete apparent improvement in three cases, marked in five, and moderate in two. GAIS was very much improved in 4/10, much improved in 4/10, and improved in 2/10. Mild transient erythema or edema occurred in 6/10; no persistent adverse events occurred.
Conclusion:
This illustrative, hypothesis-generating series documents practical 532-nm parameters across diverse superficial facial vascular phenotypes, with favorable short-term outcomes and acceptable tolerability; it is not intended to establish efficacy. Confirmation requires prospective, consecutive cohorts with standardized imaging and longer follow-up.