Exploring the Perspectives, Knowledge and Attitudes Toward the “MASH-Cardiovascular Multidisciplinary Programme” of Subjects With Metabolic Dysfunction-Associated Steatohepatitis: A Qualitative Case Study Protocol

In Spain, the management of metabolic dysfunction-associated steatohepatitis (MASH) through lifestyle changes faces challenges due to poor patient adherence, partly explained by a lack of knowledge and insufficient support from healthcare professionals. Multidisciplinary approaches involving hepatology, endocrinology, gastroenterology, nursing, psychology, dietetics, and nutrition have shown effectiveness. In our center, a one-year multidisciplinary structured programme provides a personalized care for MASH and associated cardiovascular risk management. Incorporating the perceptions of the patients into lifestyle interventions may enhance treatment outcomes. The aim of this study is to explore the perceptions, attitudes, needs, and knowledge of the patients with MASH participating in the multidisciplinary MASH-Cardiovascular programme (MASH-CVP) at our hospital. This qualitative study will use semi-structured interviews at two time points: baseline and after completion (12 months) of the MASH-CVP. Interviews will be recorded, transcribed, and analyzed using thematic content analysis. The sample size will be determined by saturation analysis. A pilot study will ensure the interview guide clarity and relevance. The study will provide insights into the perceptions, expectations, attitudes, needs, and knowledge of the patients participating in the MASH-CVP at HSCSP. The findings are expected to inform improvements in the implementation of multidisciplinary care interventions, as well as enhance communication and engagement between healthcare professionals and patients. Future research should focus on exploring barriers and facilitators of implementing these tailored interventions in broader settings, while also incorporating the voices and perceptions of the patients to improve effective communication and engagement with MASH treatment.