Exploring the outcome and safety of Ayurvedic treatments for dry eye disease: A protocol for systematic review
Navya Pavithran, P. Sreenadh, Deepak PawarAbstract
BACKGROUND:
Dry eye disease (DED) is a common ocular disorder characterized by tear film instability, visual disturbances, and surface damage, with a global prevalence ranging from 5% to 50%, particularly affecting females and worsening with age. Conventional treatments, such as artificial tears, offer limited long-term efficacy and may have side effects. Ayurveda describes a similar condition,
DATA SOURCE:
A systematic review protocol registered with International Prospective Register of Systematic Reviews (CRD42025631160) will include electronic searches in PubMed, the Cochrane Library, the AYUSH Research Portal, and other relevant databases using specific search terms related to DED and Ayurvedic treatments.
MATERIALS AND METHODS:
This review will include randomized controlled trials (RCTs), quasi-RCTS, and controlled clinical trials, while excluding observational studies, case reports, and animal studies. Participants diagnosed with
RESULTS:
The findings will systematically evaluate Ayurvedic therapies for DED and identify effective interventions.
CONCLUSION:
This review aims to integrate Ayurvedic interventions, support evidence-based clinical decisions, and guide policymakers in developing treatment guidelines.