DOI: 10.1039/d6dt01513a ISSN: 1477-9226
Expanding the scope of platinum–NHC complexes:
trans
-Pt(
ii
) and Pt(0) architectures for ovarian cancer treatment
Lorenzo Rodighiero, Anna Smoczyńska, Eleonora Botter, Eleonora Casillo, Benon P. Maliszewski, Maciej Kubicki, Cezary Pietraszuk, Flavio Rizzolio, Catherine S. J. Cazin, Sylwia Ostrowska, Steven P. Nolan, Thomas Scattolin We report novel trans -Pt(II)–NHC and Pt(0)–NHC complexes with potent activity against ovarian cancer, including cisplatin-resistant cells, and promising selectivity toward cancer cells.