Evaluation of Myopic Macular Function and Structure
Yousra A T Farweez, Amany A El-Shazly, Ahmed A Mohamed- General Medicine
Purpose
to assess the functional and structural changes in non-pathologic myopia in relation to the degree of myopia.
Methods
Cross sectional study of myopic patients. Our participants are classified into age matched four groups according to the degree of their spherical equivalent (SE): emmetropia, mild myopia; moderate myopia and high myopia. Participants underwent full ophthalmological examination, axial length (AL) measurement, Spectral domain optical coherence tomography and multifocal ERG (mf-ERG).
Results
Central foveal thickness showed significant thinning among the control participants in comparison to myopes, while inner and outer macular ring thicknesses were significantly thicker in the control participants than myopic ones. Subfoveal, inner and outer macular ring choroidal thickness were significantly thicker in the controls than myopes. Mf-ERG retinal response density [RRD] and P1 amplitudes of the three rings (R1-R3) were significantly higher in the control participants than myopic ones while P1 latency showed significant delay in the myopes in comparison to their control participants.
Conclusion
Macular thickness is related to the degree of refractive error, AL, choroidal thickness and multifocal changes in myopic patients. We should consider the correlation between functional and structural alterations in the macula when interpreting retinal structure in the assessment of macular diseases in the context of refractive errors.