DOI: 10.1371/journal.pone.0353082 ISSN: 1932-6203

Ensuring research continuity during crises: A scoping review

Lili Zeidan, Sarah Kamareddine, Macy Zaatar, Mohamad Sadek Zoghbi, Shahinda Hammoud, Hebatalla Shamseldin, Ola El Zein, Makram Halawani, May Awar Ammar, Elie A. Akl

Background

During crises, both challenging circumstances and uncertainty threaten the continuity of research operations. Research projects, research institutions and funders need to implement strategies to ensure research continuity.

Objective

To scope the literature on challenges to research continuity and strategies for ensuring research continuity during crises.

Methods

We followed standard scoping review methodology and reported findings in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines. We included quantitative, qualitative, and mixed-methods primary studies on our topic across all research disciplines and types of crises. We searched MEDLINE (OVID) and Scopus databases (January 2000 to January 2026). We abstracted data on study characteristics, challenges, mitigation strategies, and the role of funders. We summarized categorical data descriptively and analyzed qualitative data thematically presenting our findings in narrative and tabular formats.

Results

Out of 22,002 captured citations, we identified 112 eligible studies. Most studies focused on pandemic-related crises (91%), mostly related to clinical research (47%) and social sciences (46%), and were conducted predominantly in high-income countries (80%). Challenges occurred at the project (81%), institutional (27%), and funder (15%) levels. The most common challenges for these levels were respectively project suspensions (58%), lack of institutional support (14%), and poor or no research funding (12%). Key mitigation strategies were flexible research operations (80%), adjustments to institutional policies and governance (25%), and implementing strategic interventions (31%). Funders contributed to research continuity, primarily through financial flexibility (56%) and supporting adaptations (39%).

Conclusion

This scoping review maps the key challenges, strategies, and funder roles in sustaining research during crises. Findings highlight the need for flexible, resilient, and well-coordinated research systems across multiple levels. Future research should evaluate the long-term effectiveness of these strategies.

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