DOI: 10.1039/d6pm00489j ISSN: 2976-8713

Enhancement of transdermal permeation of atorvastatin calcium from a cellulose-based matrix-type patch using essential oils as a penetration enhancer

Baishali Roy, Md Sahil Reza, Piu Jana, Sanjukta Sen, Sreejan Manna, Ranabir Sahu, Tarun Kumar Dua, Paramita Paul, Nilimanka Das, Gouranga Nandi

The main objective of the study was to enhance the transdermal penetration of atorvastatin calcium, having poor oral bioavailability due to poor water solubility and high first-pass metabolism, using essential oils such as eucalyptus and lemon oil.

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