DOI: 10.1039/d6ra03993f ISSN: 2046-2069
Enhanced in vitro permeability of curcuminoids and ar-turmerone using microemulsions of menthol-based hydrophobic deep eutectic solvents
Nuntika Wangpradit, Fonthip Makkliang, Arpa Petchsomrit, Gorawit YusakulMenthol-based HDES microemulsions markedly enhanced curcumin permeation. CL2MDO (menthol : dodecanoic acid, 2 : 1 mole ratio) achieved 116 µg cm −2 at 12 h, outperforming the conventional oleic-acid-based microemulsion.