DOI: 10.1039/d6dt01248e ISSN: 1477-9226

Engineering of a Zn-based core–shell MOF for antitumor activity

Yu Shi, Enpei Zhao, Qianru Ye, Liyuan Sang, Saif Mareeha, Heng Liu, Bing Wang, Jie Shen, Wenxin Lin, Quan Hu

A ZIF-8 shell was grown on the surface of medi-MOF-1 to construct the core–shell MOF medi-MOF-1@ZIF-8 (MZ). MZ was loaded with DOX and CIP to obtain MZDC, which inhibited 4T1 cell growth and migration, showing potential for tumor treatment.

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