Endothelial Cell Loss and Intraocular Pressure Changes Following Hydroimplantation of a Foldable Posterior Chamber Intraocular Lens After Uneventful Phacoemulsification
Ayan Mitra, Shilpi Bose, Chiranjib SarkarAbstract
Aim:
To evaluate endothelial cell loss and intraocular pressure changes following hydro-implantation of a foldable posterior chamber intraocular lens after uneventful phacoemulsification in a teaching hospital in Eastern India.
Materials and Methods:
A prospective study was conducted with 175 patients who presented with cataract at out-patient department of Ophthalmology at KPC medical college, Kolkata. Phacoemulsification by single surgeon with similar steps were performed in all patients and posterior chamber intraocular lens was implanted in balanced salt solution which is also known as hydro-implantation technique. Detailed preoperative and postoperative evaluation was done on postoperative day 1, day 7, 2 nd week and end of 6 th week. Patient age, sex. laterality, cataract density grading, surgical time and cumulative dissipated energy was observed. Intraocular pressure was observed preoperatively as well as on postoperative visits on day 1, day 7, 2 nd week and end of 6 th week and compared. Endothelial cell density was observed preoperatively and postoperatively at the end of 6 th week and compared.
Results:
The mean percentage of endothelial cell density loss was 2.57% with SD of 4.651 representing individual patient-level percentage loss at end of 6 th week. The mean intraocular pressure on postoperative first day visit was 16.21 ± 2.05 mmHg which decreased to preoperative values within one to two weeks.
Conclusion:
In this single-arm prospective cohort, hydro-implantation was associated with a small transient increase in intraocular pressure on postoperative day 1 and a mean individual patient-level endothelial cell loss of 2.57% at 6 weeks. Comparative safety, efficacy, and cost-effectiveness cannot be determined in the absence of an ophthalmic viscosurgical device (OVD)-assisted control group.