DOI: 10.1097/icb.0000000000001908 ISSN: 1935-1089

Endogenous Streptococcus Anginosus Endophthalmitis: A Case Report and Review of the Literature

Nish Patel, Tejaswini Matsyaraja, Marten R. Hawkins, Shilpa Kodati

Purpose:

To report a case of unilateral endogenous Streptococcus anginosus endophthalmitis in order to improve timely recognition and treatment strategies for similar presentations.

Methods:

A retrospective review of the electronic medical record of one patient was performed from September 2024 through December 2024.

Results:

A 50-year-old healthy male presented with a unilateral hypopyon and dense vitreous opacities. The patient was found to have evidence of systemic infection and endophthalmitis secondary to S. anginosus; specifically, the patient was found to have a large subcarinal mass as well as abscesses in the left cerebrum, both of which were positive for S. anginosus . The patient underwent treatment with intravitreal and systemic antibiotics as well as pars plana vitrectomy.

Conclusion:

S. anginosus endophthalmitis in the setting of a confirmed primary mediastinal infection has not previously been reported. Our patient had a particularly virulent presentation of S. anginosus endophthalmitis, and the ophthalmic findings led to the diagnosis of a systemic infection. A thorough systemic evaluation of patients with suspected endogenous endophthalmitis should be pursued, and a seemingly noncontributory medical history can prove to be significant.

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