Empathy Levels Among Medical Students at a Romanian University: A Cross-Sectional Study Using the Jefferson Scale of Empathy

Background/Objectives: Empathy is a fundamental component of patient-centered care and plays a critical role in the physician–patient relationship. This study aimed to evaluate empathy levels among undergraduate medical students at a medical university in Romania, examined from a Medical Humanities perspective, and to analyze how these scores are distributed according to gender, academic year, clinical stage, and direct experience with patient contact. Methods: A descriptive, cross-sectional study was conducted among 209 undergraduate medical students across all six academic years. Empathy levels were assessed using the Romanian-language version of the Jefferson Scale of Empathy—Student Version (JSE-S). Differences in empathy scores were analyzed using independent samples t-tests and a one-way analysis of variance (ANOVA) with Tukey Honestly Significant Difference (HSD) post hoc comparisons. Statistical significance was set at an alpha level of less than 0.05. Results: Internal consistency of the JSE-S total scale was good (Cronbach’s α = 0.829). The overall mean total JSE-S score was 107.34 ± 14.34. Female students demonstrated significantly higher empathy scores compared to male students (109.92 ± 13.10 versus 99.37 ± 15.20; t = 4.450; p < 0.001; Cohen’s d = 0.77). No statistically significant differences were found between preclinical and clinical stage students (106.84 ± 14.75 versus 108.98 ± 12.90; p = 0.363; Cohen’s d = −0.15), between students with and without direct patient contact (108.20 ± 14.14 versus 104.48 ± 14.78; p = 0.115; Cohen’s d = 0.26), or across the six academic years (F = 1.614; p = 0.158; partial η2 = 0.038). Conclusions: Medical students demonstrated moderate-to-high empathy levels, with gender representing the only statistically significant demographic factor. The absence of major differences across academic-year cohorts and clinical exposure suggests that empathy levels were comparably represented across the different stages of training within this cross-sectional sample. These findings contribute descriptive data on empathy levels among Romanian medical students and highlight gender as the main factor associated with variation in empathy scores in this sample.