DOI: 10.26634/jchem.4.3.21569 ISSN: 2583-9101

Efficient synthesis of losartan potassium: An improved two-step method

Rajendra Sonawane Prashant
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A highly effective and high-yield synthetic approach for producing Losartan Potassium in two steps is presented. The method begins with Trityl Losartan, which undergoes a reaction with Potassium Tertiary Butoxide in Tetrahydrofuran to yield Losartan Potassium. Subsequently, purification using Isopropyl alcohol results in the production of pure Losartan Potassium.

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