Effects of the Solvent and the Nucleophile on the Photochemical Synthesis of Azepines

Abstract

The research focused on the photolysis of ortho‐ and para‐substituted aryl azides and the preparation of 2‐arylamino‐substituted azepines. The best results were achieved in 1,4‐dioxane for ortho‐substituted azides and in ethanol for para‐substituted azides, respectively. It was found that reactions with arylamines, which have electron‐donating groups, typically produce higher yields of heterocycles than those with electron‐withdrawing groups.