Effects of Dynamic Resistance Training on Arterial Stiffness Assessed by Pulse Wave Velocity: A Systematic Review and Meta-Analysis
Ricardo Cordeiro, Michel Oliveira, Bruno Oliveira, Sabrina Santos, Jeferson Rocha, José Cristiano Paes Leme da Silva, Paulo FarinattiArterial stiffness predicts cardiovascular risk, but the chronic effects of dynamic resistance training (RT) remain unclear. This meta-analysis quantified RT effects on arterial stiffness assessed by pulse wave velocity (PWV) and explored moderators. Databases were searched through 26 August 2026. Studies included adults (≥19 years) undergoing RT with pre–post PWV data. Random-effects models were used. Fourteen trials included 20 RT interventions and 10 controlled comparisons (n = 379: 278 RT and 101 control participants; age range 19–63 years; mean age, 33.3 ± 14.3 and 32.4 ± 15.1 years in the RT and control groups, respectively; baseline blood pressure range, 108/64 to 137/90 mmHg). Participants were predominantly physically inactive. Assuming a pre–post correlation of 0.50, pooled effects were non-significant for central PWV (g = −0.002; 95% CI, −0.213 to 0.209; p = 0.985), mixed PWV (g = −0.548; 95% CI, −1.168 to 0.071; p = 0.083), peripheral PWV (g = −0.110; 95% CI, −0.436 to 0.217; p = 0.511), and overall PWV (g = −0.102; 95% CI, −0.281 to 0.077; p = 0.265). Heterogeneity ranged from 43% to 70%. Sensitivity analyses using correlations of 0.30 and 0.70 did not alter statistical significance. Most moderator tests, including those involving participant characteristics and FITT-VP components, were not statistically significant. The few significant subgroup differences were exploratory and arose from small, unbalanced groups without multiplicity adjustment, precluding firm conclusions. Dynamic RT was not associated with a significant change in arterial stiffness; however, imprecision and heterogeneity preclude claims of equivalence or absence of physiological effects. Registration: PROSPERO CRD42022377587.