DOI: 10.1039/d6sc03439j ISSN: 2041-6520

Dynamic coordination and reconstruction-induced chemiluminescence in chiral covalent organic frameworks for enantioselective sensing

Yanhui Zhong, Shuyi Wang, Xiaoyu Wang, Zian Lin

Chiral COFs were constructed via reversible cysteine-Co 2+ coordination, enabling recognition‑triggered reconstruction and reconstruction‑induced response. Chiral drugs displace cysteine, triggering interface reconstruction and CL modulation.

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