DOI: 10.1039/d6sc03337g ISSN: 2041-6520
Direct access to 2-imidazolines from unactivated alkenes
Stefanie Schiele, Ann-Sophie K. Paschke, Giorgia Romiti, Bill MorandiUnactivated alkenes are converted to 2-imidazolines. The combination of ammonia and a hypervalent iodine reagent achieves the cleavage of the alkene's double bond. Ethylenediamine intercepts the resulting imine and oxidation furnishes 2-imidazoline.