DOI: 10.1001/jamaneurol.2026.1659 ISSN: 2168-6149

Diminishing Returns of Novel Autoantibody Discovery in Encephalitis

Naoki Takegami, Gregory S. Day, Frank Leypoldt, Sarosh R. Irani

This Viewpoint describes a plateau in the discovery of clinically meaningful autoantibodies in autoimmune encephalitis (AE) and suggests efforts that are likely to offer greater benefits to patients living with AE.

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