DOI: 10.1039/d6ra03517e ISSN: 2046-2069
Dihydropyrimidinone–isatin hybrids as potent inducers of cell-cycle arrest and caspase-dependent apoptosis in MV4-11 acute myeloid leukemia cells
Preeti, Asif Raza, Jashandeep Kaur, Arun K. Sharma, Vipan Kumar1 H -1,2,3-triazole-linked DHPM–isatin hybrids exhibit potent antiproliferative activity against acute myeloid leukemia via ROS-induced oxidative stress, G2/M cell cycle arrest, and caspase-mediated apoptosis.