DOI: 10.32322/jhsm.1947771 ISSN: 2636-8579

Diffusion-weighted imaging of the placenta and fetal brain in fetal growth restriction: a cross-sectional study

Elif Yaşar, Fulya Başkak, Özge Kahramanoğlu
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Aims: The aim of this study is to evaluate placental and fetal brain diffusion-weighted imaging (DWI) findings in fetuses with fetal growth restriction (FGR) and to investigate whether placental diffusion abnormalities are accompanied by alterations in fetal brain microstructure. Methods: In this retrospective study, 54 fetuses (25 FGR, 29 controls) who underwent third-trimester fetal magnetic resonance imaging were included. DWI was performed and apparent diffusion coefficient (ADC) values were measured in the placenta (central and peripheral regions) and fetal brain. Group comparisons were performed using appropriate statistical tests, and gestational age (GA)-adjusted analyses were conducted using analysis of covariance.Results: Placental ADC values were significantly lower in the FGR group than controls in both central and peripheral regions (p

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