Di‐ tert‐ Butyl Peroxide: An Effective Oxidizing Agent for Oxidative Transformations in Organic Synthesis
Apurva Dabas, Samriddhi Shukla, Khushi Ray, Priyanshu Singh, Anil Kumar Singh, Jaggi Lal, Richa Arora, Yogesh KumarABSTRACT
DTBP (Di‐ tert ‐butyl peroxide)‐mediated oxidative reactions represent an attractive approach for synthetic organic chemistry. This review highlights the recent advancements of oxidative strategies for synthetic chemistry, like C─H functionalization and other reactions. Recent studies have highlighted the efficacy of DTBP as an oxidant in activating sp 3 C─H activation and functionalization reactions. Notably, the use of the DTBP approach, which combines metal/metal‐free activation with remote C─H activation, has created a revolutionary impact in synthetic chemistry. Various DTBP‐mediated oxidative reactions are discussed with numerous examples and proposed mechanisms. This review is expected to be a short, authoritative, and comprehensive analysis of the DTBP for the chemistry community.