Development of posterior vitreous detachment after lens surgery in myopic eyes - Results from the MYOPRED study
Marlies Ullrich, Hannah Ivellio-Vellin, Domagoj Ivastinovic, Stefan Palkovits, Álvaro Fernández-Vega Sanz, Marie-José Tassignon, Francisco Poyales, Kjell G. Gundersen, Michael Amon, José L. Güell, Jérôme C. Vryghem, Rudy M.M.A. Nuijts, Caroline Pilwachs, Andreas Gleiss, Oliver Findl,PURPOSE:
To evaluate the preoperative posterior vitreous detachment (PVD) status and PVD progression in myopic eyes without preexisting complete PVD after lens surgery.
SETTING:
10 European study centers
DESIGN:
Prospective observational multicenter study
METHODS:
Eyes with an axial length of ≥25.0 mm scheduled for phacoemulsification were included. Preoperatively and at each visit, the PVD status was assessed by optical coherence tomography, at certain sites using additional ultrasonography. All patients had a follow-up visit 2 months postoperatively, those without preoperative complete PVD additionally at 6 and 12 months or until presence of complete PVD.
RESULTS:
In the analysis, 968 eyes (600 study eyes, 368 eligible fellow eyes) of 600 patients were considered. Mean age was 64.8±9.9 years (range 23–92), 290 (48.3%) were female, 310 (51.7%) male. At baseline, PVD was complete in 512 (52.9%) eyes, incomplete in 256 (26.4%), no PVD in 85 (8.8%) and ‘not decisive’ in 115 (11.9%). Of the eyes with no or incomplete PVD preoperatively, 9.9–12.6% developed a complete PVD by 2 months, 25.5% by 6 and 40.2% by 12 months (n=327). The hazard ratio for progression to complete PVD was 1.37 (CI 1.10–1.69,
CONCLUSIONS:
Four out of 10 myopic eyes with no or incomplete PVD preoperatively progressed to complete PVD within 1 year after phacoemulsification. Progression to complete PVD was associated with patient age and axial length.