Development of a Piezo Biosensor for Pathogen-specific Biopolymer Detection Using Polymer Piezo Films: Investigation of Detection Characteristics of Piezo Biosensors and Self-assembled BaTiO3/Polymer Composite Materials

Infectious diseases are rapidly spreading across the globe. In this chapter, we propose a piezoelectric biosensor as an application of polymeric materials with dielectric properties. We emphasize the importance of combining isothermal genetic diagnostics with a piezoelectric biosensor that uses a piezoelectric polymer film, as it has significant potential for the early detection of infectious diseases. It is possible that piezoelectric biosensors using β-PVDF detect biopolymers through the relaxation behavior of β-PVDF. To solve the problems of β-PVDF, we developed self-assembled BaTiO3/polymer composite materials and applied the composite materials to the piezoelectric biosensors. The presence of a BaTiO3/polymer/BaTiO3 heterointerface within the self-assembled BaTiO3 aggregates forms an electric dipole, which plays an important role in improving the dielectric properties and piezoelectricity. It also leads to an improvement in the elastic constant. The piezoelectric biosensor using the self-assembled BaTiO3/PVDF composite material has improved temperature characteristics.