DOI: 10.52711/0974-360x.2024.00165 ISSN: 0974-360X
Development and Validation of a UV Spectrophotometric Method for determination of Ondansetron hydrochloride in Bulk and Tablet Dosage Form
Prathamesh L. Shirole, Dhanashree P. Sanap, Kisan R. Jadhav- Pharmacology (medical)
- Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
Our goal is to create and validate a UV Spectrophotometric method for estimating the Ondansetron HCL. According to ICH criteria, the procedure was verified. At 248.8nm, ondansetron has its highest absorption. Between 2 and 22g/ml, the linearity was noted. Recovery studies supported the analysis' findings. The findings of the validation parameters showed that the suggested technique was determined to be exact, precise, repeatable, sensitive, and appropriate for regular quality control analysis for estimation of ondansetron hydrochloride in solid dose formulation.