DOI: 10.1039/d6pm00165c ISSN: 2976-8713

Development and evaluation of carbomer-based gel matrix pellets for improved bioavailability and intestinal retention of menbutone

Sajid Hussain, Shinan Jiang, Peng Jin, Luqiu Feng, Min Cheng, Tengli Zhang, Huajun Luo, Anabel Sorolla, Lei Luo

Carbomer-based menbutone pellets prolonged intestinal retention, delayed peak exposure, and increased systemic exposure in rats compared with unformulated powder.

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