Development and comparative pharmacokinetic evaluation of iodine-125- and fluorine-18-labelled analogues of 4-(benzo[ d ]thiazol-2-yl)phenylboronic acid for boron neutron capture therapy

Radiohalogenated BTPB analogues exhibit distinct in vivo distributions. [ ¹⁸ F]FPBT shows early brain uptake and increasing tumour-to-brain contrast, supporting further evaluation as a candidate PET imaging analogue.