Detection of miRNA-21 in the early stages of lung and ovarian cancers using a fluorescent biosensor designed through ssDNA binding with a [Ru(bpy)
                    <sub>2</sub>
                    (fmp)](ClO
                    <sub>4</sub>

doi:10.1039/d6ma00857g

DOI: 10.1039/d6ma00857g ISSN: 2633-5409

Detection of miRNA-21 in the early stages of lung and ovarian cancers using a fluorescent biosensor designed through ssDNA binding with a [Ru(bpy) ₂ (fmp)](ClO ₄

Sheida Zoughi, Farnoush Faridbod, Ahmad Amiri

An enzyme-free fluorescent biosensor based on an ssDNA–ruthenium complex enables sensitive miR-21 detection through target-induced fluorescence quenching, with successful application to plasma and cancer cell samples.

Outline

Detection of miRNA-21 in the early stages of lung and ovarian cancers using a fluorescent biosensor designed through ssDNA binding with a [Ru(bpy) ₂ (fmp)](ClO ₄

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Detection of miRNA-21 in the early stages of lung and ovarian cancers using a fluorescent biosensor designed through ssDNA binding with a [Ru(bpy) 2 (fmp)](ClO 4

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Detection of miRNA-21 in the early stages of lung and ovarian cancers using a fluorescent biosensor designed through ssDNA binding with a [Ru(bpy) ₂ (fmp)](ClO ₄