DOI: 10.1039/d6ra06656a ISSN: 2046-2069
Design, synthesis, and preliminary anticancer evaluation of diphenylpropan-1-one derivatives: in vitro , in vivo and in silico
Asim Najmi, Md Shamsher Alam, Waquar Ahsan, Khalid Zoghebi, Syam Mohan, Neelaveni Thangavel, Manal M. E. Taha, Mohammad Ashafaq, Md. Afroz Bakht, Abdulkarim Meraya, Mohammed AlbrattyA series of diphenylpropan-1-ones (DPP) was synthesized and screened for preliminary anticancer activity, leading to the identification of compound 4h as a promising anticancer lead through in vitro , in vivo , and exploratory in silico investigations.