Design, synthesis and network pharmacology-integrated evaluation of benzenesulfonamides as potential Dickkopf-1 (Dkk-1)-targeting anticancer candidates

The current study is focused on designing of sulfanilamide derivatives and to study their potential against carbonic anhydrase II, pancreatic elastase, Dickkopf-1 (Dkk1) and LRP6 proteins, which are potential anti-cancer targets for various cancers.