DOI: 10.1039/d6md00440g ISSN: 2632-8682

Design, synthesis, and nanomedicine based delivery of benzimidazole derivatives with promising antiproliferative activity

Mai Montaser Abdullah, Rania M. Hathout, Reham S. Elezaby, Nourhan M. Abdelmaksoud, Mahmoud M. Elaasser, Dalal A. Abou El Ella, Mai Adel

Novel benzimidazole derivatives showed potent antiproliferative activity, with 16a surpassing reference drugs. Nanoparticle formulations of 16a and 17b enhanced efficacy while preserving safety, underscoring their promise in targeted cancer therapy.

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