DOI: 10.1039/d6ra01662f ISSN: 2046-2069

Design, synthesis, and evaluation of pyrano[3,2- c ]coumarin derivatives for simultaneous targeting of amyloid-β 42 and acetylcholinesterase in transgen

Saurabh Sharma, Shalini Sharma, Vaishali Raghuvanshi, Sandhya Kumari, Sher Singh, Ray J. Butcher, Saripella Srikrishna, Diksha Katiyar

Facile Fe(

iii
)-catalyzed access to pyrano[3,2- c ]coumarins as promising anti-Alzheimer's agents targeting amyloid-β 42 aggregation (Aβ 42 ) and acetylcholinesterase (AChE) in a transgenic AD model of Drosophila .

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