Design, synthesis, and docking analysis of benzene sulfonamide-[1,4]benzoxazepine hybrids as acetylcholinesterase and butyrylcholinesterase inhibitors

Compound 12j was evaluated for its inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), showing preferential inhibition of BChE over AChE with selectivity index = 10.37.