DOI: 10.1021/acsabm.6c01369 ISSN: 2576-6422

Design of Dual-Path Antibacterial Aluminum Alloy Based on ZnO Sputtering and Surface Roughness Control

Xia Luo, Zijun Liu, Yaqun Yao, Jia Meng, Kunfu Zhu, Huiwei Feng, Feng Xue, Yanyan Jiang

Abstract

Antibacterial alloys based on aluminum alloys have become a hot topic. However, most existing research is limited to a single antibacterial mechanism and may suffer from insufficient long-term efficacy, making it difficult to meet the requirements of large-scale production and applications in diverse scenarios. Therefore, the development of a synergistic, multi-mechanism antibacterial modification strategy for aluminum alloys is urgently needed. In this study, a dual-mechanism antibacterial aluminum alloy was developed by combining surface-structure-assisted antibacterial activity with ZnO-mediated antibacterial activity. By adjusting various process parameters, the surface roughness of the aluminum alloy and the microstructure of ZnO were regulated. This study systematically investigated the effects of aluminum-alloy surface roughness and ZnO microstructure on the antibacterial performance of the composite system. In vitro antibacterial test results showed that aluminum alloy subjected to the dual-mechanism modification exhibited excellent antibacterial activity: the antibacterial rate against E. coli and S. aureus reached 95 and 90%, respectively. This study provides a strategy to construct the dual-pathway synergistic antibacterial aluminum alloy, which possesses great potential in applications such as food processing, medical devices, and public health.