DOI: 10.1093/biolre/ioag206 ISSN: 0006-3363
DELE1 is dispensable for heat-stress-induced ISR during mouse spermatogenesis but has implications for lipid metabolism
Yilan Teng, Mingxing Zhang, Zhicheng Wu, Zixuan Li, Deqiang Ding, Hongwen Zhu, Peng DaiGerm cell specific Dele1 knockout in mice fails to impair male fertility and heat stress induced integrated stress response, while proteomic profiling implicates DELE1 as a candidate modulator of germ cell lipid metabolism.