DOI: 10.1148/radiol.260656 ISSN: 0033-8419
Deep Learning–derived Bone Mineral Density and Longitudinal White Matter Microstructure and Cognitive Decline: Multi-Ethnic Study of Atherosclerosis
Sara Momtazmanesh, Quincy A. Hathaway, Michael P. Bancks, David A. Bluemke, R. Graham Barr, Wendy S. Post, Mohamad Habes, Ilya Nasrallah, Susan R. Heckbert, R. Nick Bryan, Jose A. Luchsinger, Mei Wan, Matthew Budoff, João A. C. Lima, Timothy M. Hughes, Christos Davatzikos, Shadpour DemehriLower vertebral bone mineral density from chest CT was associated with modestly accelerated white matter injury and cognitive decline, particularly among participants with diabetes, suggesting utility for detecting accelerated brain aging.