DOI: 10.1002/ejoc.202400248 ISSN: 1434-193X
Decatungstate‐Photocatalyzed Diastereoselective Dearomative Hydroalkylation of Indoles
Emeric Montinho-Inacio, Damien Bouchet, Wei-Yang Ma, Pascal Retailleau, Luc Neuville, Géraldine Masson- Organic Chemistry
- Physical and Theoretical Chemistry
In this study, we present an efficient and straightforward dearomative hydroalkylation of indoles. By utilizing alkanes or ethers as alkyl radical sources and employing TBADT as a cost‐effective photocatalyst for direct hydrogen atom transfer (HAT), we achieved successful conversion of these heterocyclic derivatives into 2‐alkylindolines with good to excellent yields and high diastereoselectivity under mild reaction conditions.