DOI: 10.1039/d6ra00546b ISSN: 2046-2069
Cyclomulberrin from Morus alba L. exerts antithrombotic effects by modulating platelet activation: an integrated network pharmacology and in vitro study
Yanqiong Guo, Rongrong He, Jing Peng, Shuguo Yuan, Yanlei Ma, Qingde LiNetwork pharmacology, docking/MD, and platelet assays reveal that cyclomulberrin from Morus alba modulates platelet activation via multi-target/multi-pathway mechanisms, conferring antithrombotic effects without affecting coagulation.