Current Landscape of Neonatal/Infant
HIV
Research: Preclinical and Translational Perspectives
L. M. Johnson, E. H. Luecke, C. A. Norton, M. L. Cottrell, G. Fouda ABSTRACT
This session of the NHP Models for HIV Prevention and Treatment: Towards Developing Pediatric Formulations workshop focused on preclinical and translational perspectives in HIV research, with an emphasis on neonatal and infant populations. This review described the outputs of this workshop session, highlighting two key strategies to advance HIV treatment and prevention in young children: the development of novel long‐acting (LA) antiretroviral (ARV) formulations for children living with HIV (CLWH) and the implementation of immune‐based interventions to prevent vertical HIV transmission. Both approaches demonstrate the critical importance and value of preclinical studies in nonhuman primate (NHP) models to support the advancement of these technologies, with the ultimate goal of improved health outcomes in pediatric populations.