CT-guided percutaneous lung biopsy under calm breathing
Meiru Wen, Ailin Chen, Zhiqiang Peng, Qimin Li, Songling Zhang, Shiliang Huang, Xiaofei Tang, Jing Liu, Meili LiAbstract
Objectives
To investigate the use of syringe needle-assisted localization to enable patients to undergo CT-guided percutaneous lung biopsy performed under calm breathing. This approach was developed to facilitate CT-guided lung biopsy in patients who have difficulty performing breath-holding maneuvers and to improve procedural feasibility under calm breathing conditions.
Methods
A total of 200 patients who underwent CT-guided percutaneous lung biopsy were included and randomly allocated to either a syringe needle-assisted calm breathing group (n=100) or a conventional breath-holding group (n=100). Procedural outcomes, including puncture success rate, procedure-related complications (pneumothorax, pulmonary hemorrhage, hemothorax, chest wall hematoma, and air embolism), and the number of needle adjustments, were collected and compared between the two groups.
Results
No statistically significant differences were detected in puncture success rate or complication rates. The calm breathing group showed a tendency toward fewer needle adjustments, although the statistical interpretation differed between the primary mean-based analysis and the non-parametric sensitivity analysis.
Conclusions
CT-guided percutaneous lung biopsy under calm breathing with syringe needle-assisted localization was feasible in the present study and may be useful for patients who have difficulty cooperating with breath-holding instructions.