CROSS SECTIONAL STUDY ON CAUDA70 SCORE AND ITS RELATION WITH TREATMENT OUTCOMES IN ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE AT IRD, SMS MEDICAL COLLEGE, JAIPUR

Background: Acute exacerbation of COPD can be attributed to varying aetiologies. AECOPD has been linked to certain variables that determine prognosis. CAUDA70 score uses 6 easily measurable parameters that reect the underlying multisystem involvement . This study was done to assess CAUDA70 score and its relation with treatment outcomes in patients with acute exacerbation of COPD. Methods:150 patients admitted with an acute exacerbation of COPD were included in this hospital based cross sectional study. One point was given for each of the following variable: Confusion, Acidosis (pH<7.35),Urea >7mmol/L, Dyspnoea mMRC 4, Albumin>35g/L, Age>70 years, thus yielding a six point scoring system. The outcome of the patient was correlated with the score obtained to assess prognosis. Result: Out of 150 patients , 71 patients(47.3%) obtained a score up to 2. Among these patients, 58(81.69%) recovered without ventilation whereas 13(18.30%) needed non invasive ventilation for management, none of the patients required invasive ventilation and there was no mortality. Rest 79 patients(52.6%) had a score between 3 to 6. Among these patients , 8 (10.1%) required invasive ventilation, mortality was reported among 12 (15.1%), 42(53.1%) required non invasive ventilation whereas 17(21.5%) recovered without ventilation. Higher CAUDA70 score was signicantly associated with a poorer outcome (p-value<0.001) in terms of higher no. of mortality and requirement of invasive ventilation. Conclusion: CAUDA 70 score proved to be simple and effective tool to predict the need for mechanical ventilation and prevent mortality. The ndings help in determining which patients are at high risk of in-hospital death and is useful in decisions on patient admission, discharge management and health care resource allocation.